I passed through Roanoke twice for section hikes and I can tell you that this otherwise quintessential little town has a creepy side especially around the Greyhound bus station. If this young lady wants to get on the trail, the best way is to take the bus to Blacksburg and then a shuttle (in my case, to Pearisburg with the Hiker's Heaven hostel). If she wants to go to WV, then she will have to take a Greyhound bus or Amtrak train to DC. So, her options to get out of Roanoke are limited and I would be surprised if she's not found yet.